Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836249 | 0.69 | KDM4E (0.44) | CA12CA1CA2CA9CA4 | |
| SCHEMBL448460 | 0.69 | KMT2A (0.39) | CA12CA1CA2CA9CA4 | |
| SCHEMBL21910775 | 0.68 | CA9 (0.48) | CA12CA1CA2CA9CA4 | |
| SCHEMBL29522682 | 0.67 | MEN1 (0.52) | KDM4ELMNABCHEKMT2AKCNQ2 | |
| SCHEMBL12997894 | 0.67 | MEN1 (0.52) | KDM4ELMNABCHEKMT2AKCNQ2 | |
| SCHEMBL12997896 | 0.67 | MEN1 (0.52) | KDM4ELMNABCHEKMT2AKCNQ2 | |
| SCHEMBL1855552 | 0.67 | MEN1 (0.52) | KDM4ELMNABCHEKMT2AKCNQ2 | |
| Ammonia Solution, Strong SCHEMBL446104 | 0.67 | KMT2A (0.38) | CA12CA1CA2CA9CA4 | |
| SCHEMBL11482321 | 0.64 | MEN1 (0.48) | CA1CA2CA9CA7KDM4E | |
| SCHEMBL883417 | 0.62 | DAO (0.43) | CA1CA2CA9CA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003102151-A2 | MODULATING CELL DIFFERENTIATION AND TREATING MYELOPROLIFERTIVE DISORDERS WITH JNK/MKK INHIBITORS | CELGENE CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |