Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL446104 | 0.98 | KMT2A (0.38) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL5523699 | 0.75 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL17169742 | 0.75 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL26048255 | 0.75 | KMT2A (0.39) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL14425421 | 0.75 | CA1 (0.41) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL7685977 | 0.75 | KMT2A (0.35) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL428285 | 0.75 | CA1 (0.45) | CA12CA1CA2CA9CA4 | |
| SCHEMBL21910775 | 0.75 | CA9 (0.48) | KMT2AMEN1NOX1CA12CA1 | |
| SCHEMBL26705045 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL24697302 | 0.73 | CA2 (0.44) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078091-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2024-09-12 | — | — | US | disclosed |
| US-20230350294-A1 | Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| EP-3483143-B1 | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2023-10-18 | — | — | EP | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11768434-B2 | Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-20230242495-A1 | Nitrosation Reagents and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230242495-A1 | Nitrosation Reagents and Methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| EP-4092012-A1 | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC. (US) | 2022-11-23 | — | — | EP | disclosed |
| US-20220169611-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | AMGEN INC (US) | 2022-06-02 | — | — | US | disclosed |
| US-20030195230-A1 | Substituted amine derivatives and methods of use | AMGEN INC. | 2003-10-16 | — | — | US | disclosed |
| US-20030134836-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | disclosed |
| US-20020147198-A1 | Substituted arylamine derivatives and methods of use | AMGEN INC. | 2002-10-10 | — | — | US | disclosed |
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |
| US-6300354-B1 | FOR THERAPY OF NEUROLEPTIC DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |
| CN-1312809-A | N-substituted azabicycloheptane deriratives, production and use thereof | BASF AG (DE) | 2001-09-12 | — | — | CN | disclosed |
| US-6191297-B1 | HYDROSILATION OF FUNCTIONALLIZED ALLYL COMPOUNDS, E.G. ALLYL CHLORIDE, BY HYDROGEN SILANES, E.G. DICHLOROMETHYLSILANE, USING A CATALYST OF A COMPLEX OF PLATINUM AND ONE OR MORE SULFUR-CONTAINING LIGANDS; EFFICIENCY | DEGUSSA-HULS AG (DE) | 2001-02-20 | — | — | US | disclosed |
| CN-1277607-A | 2-substituted 1,2-benzisothiazole derivatives and their use as serotonin antagonists (5-HT1A, 5-HT1b and 5-HT1D) | BASF AG (DE) | 2000-12-20 | — | — | CN | disclosed |
| CN-1241570-A | New process for preparation of organosilanes functionalised in the 3-position | DEGUSSA (DE) | 2000-01-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300892-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | MDM2, TP53, CDKN1A | KMT2A 919/4885MEN1 1267/4885NOX1 2258/4885 |
| US-20260078091-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | TP53, HIF1AN, MDM2 | KMT2A 1019/4885MEN1 3957/4885NOX1 3797/4885 |
| US-20030125339-A1 | Substituted alkylamine derivatives and methods of use | AADAC, NAT1, PIGO | KMT2A 1313/4885MEN1 1464/4885NOX1 420/4885 |
| US-20220169611-A1 | Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer | MDM2, TP53, CDKN1A | KMT2A 919/4885MEN1 1267/4885NOX1 2258/4885 |
| US-20030134836-A1 | Substituted arylamine derivatives and methods of use | NAT1, AADAC, AHR | KMT2A 1457/4885MEN1 2237/4885NOX1 204/4885 |
| US-20230242495-A1 | Nitrosation Reagents and Methods | NOS2, NOS1, NNMT | KMT2A 3043/4885MEN1 1149/4885NOX1 7/4885 |
| US-20020147198-A1 | Substituted arylamine derivatives and methods of use | NAT1, AADAC, AHR | KMT2A 1457/4885MEN1 2237/4885NOX1 204/4885 |
| US-20030195230-A1 | Substituted amine derivatives and methods of use | MAOB, HNMT, FLT4 | KMT2A 1259/4885MEN1 664/4885NOX1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.