SCHEMBL8347315

SCHEMBL8347315

CC1(P(=O)(O)O)CCCC(=O)C1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
ENO1 P06733 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11317025 0.73 SMN1; SMN2 (0.32) TSHR
SCHEMBL11420149 0.73 TSHR (0.46) TSHRCYP2C19
SCHEMBL27792298 0.71 TSHR (0.50) TSHRCYP2C19
SCHEMBL2228829 0.70
SCHEMBL11317030 0.69 ENO1 (0.31) ENO1
SCHEMBL8749 0.69
SCHEMBL13129928 0.67
SCHEMBL5740964 0.66 TRIM24 (0.40)
SCHEMBL23531315 0.66
SCHEMBL19186670 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861107-A ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER BAYER AKTIENGESELLSCHAFT (DE) 1999-01-19 US disclosed
EP-0816354-A1 Process for preparing and stabilisation of aliphatic six-membered cyclic carbonates BAYER AG (DE) 1998-01-07 EP disclosed
US-4265769-A CORROSION RESISTANCE, ANTISCALING AGENTS CIBA-GEIGY CORPORATION (US) 1981-05-05 US disclosed
US-4208344-A CORROSION RESISTANCE, ANTISCALING AGENTS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed