Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442206 | 0.86 | ADAM17 (0.56) | ADAM17POLBGAAKMT2AMEN1 | |
| SCHEMBL21768166 | 0.83 | ADAM17 (0.48) | ADAM17DRD2DRD4POLBMAPK1 | |
| SCHEMBL14991264 | 0.83 | GAA (0.47) | ADAM17POLBMAPK1ALDH1A1LMNA | |
| SCHEMBL6765847 | 0.82 | ADAM17 (0.46) | ADAM17DRD2DRD4 | |
| SCHEMBL31039229 | 0.82 | ADAM17 (0.45) | ADAM17POLBGAAKMT2AMEN1 | |
| SCHEMBL31298892 | 0.81 | KDM4E (0.47) | ADAM17POLBALDH1A1GAAKMT2A | |
| SCHEMBL20773874 | 0.81 | PARK7 (0.50) | ADAM17POLBGAAKMT2AMEN1 | |
| SCHEMBL31039203 | 0.81 | ADAM17 (0.46) | ADAM17POLBGAAKMT2AMEN1 | |
| SCHEMBL29507053 | 0.81 | PARK7 (0.50) | ADAM17POLBGAAKMT2AMEN1 | |
| SCHEMBL28242054 | 0.81 | ADAM17 (0.46) | ADAM17POLBGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014365-A1 | PHTHALIMIDE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |