Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 4/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 9/20 | 0.41 |
| ▸ | RARG | P13631 | 8/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347051 | 1.00 | RXRA (0.41) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8347370 | 0.91 | PLK1 (0.44) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8347040 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8352417 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8347443 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8349942 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8347100 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8345697 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8345600 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB | |
| SCHEMBL8353212 | 0.90 | PLK1 (0.46) | RXRARXRBRXRGHNF4ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | disclosed |