Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.55 |
| ▸ | F10 | P00742 | 14/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7458383 | 0.85 | F10 (0.55) | F2F10PRSS1TMPRSS6 | |
| SCHEMBL7364895 | 0.83 | F10 (0.54) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7460186 | 0.79 | F10 (0.51) | F2F10PRSS1TMPRSS6 | |
| SCHEMBL7360591 | 0.77 | F10 (0.67) | F2F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL8345839 | 0.76 | F10 (0.87) | F2F10PRSS1 | |
| Ethylene Glycol SCHEMBL27959589 | 0.74 | ABCB1 (0.43) | — | |
| SCHEMBL7361912 | 0.73 | FFAR1 (0.53) | — | |
| Methyl Benzoate SCHEMBL7560351 | 0.73 | F2 (0.55) | F2F10PRSS1TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL8345456 | 0.72 | F10 (0.90) | F2F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL8343408 | 0.72 | F10 (0.89) | F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |