Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527410 | 0.82 | FFAR1 (0.48) | FFAR1CNR1LMNAFFAR4CNR2 | |
| SCHEMBL7361747 | 0.82 | FFAR1 (0.52) | FFAR1FFAR4CNR2MAOBHTT | |
| Ethylene Glycol SCHEMBL27959589 | 0.80 | ABCB1 (0.43) | FFAR1KCNA5LMNAMAOB | |
| SCHEMBL5089141 | 0.78 | FFAR1 (0.48) | FFAR1CNR1LMNAFFAR4CNR2 | |
| SCHEMBL6288702 | 0.77 | KCNA5 (0.53) | FFAR1KCNA5CNR1CNR2GPR139 | |
| Hydrochloric Acid SCHEMBL5098915 | 0.77 | FFAR1 (0.47) | FFAR1CNR1LMNAFFAR4CNR2 | |
| SCHEMBL24387800 | 0.76 | KCNA5 (0.52) | FFAR1KCNA5CNR1CNR2GPR139 | |
| SCHEMBL7363315 | 0.75 | F10 (0.60) | FFAR1KCNA5FFAR4 | |
| SCHEMBL11687261 | 0.75 | FFAR1 (0.45) | FFAR1CNR1LMNAFFAR4CNR2 | |
| SCHEMBL7361915 | 0.74 | NLRP3 (0.48) | FFAR1LMNAFFAR4GPR34PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942544-A | α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0892780-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030971-A1 | M-AMIDINO PHENYL ANALOGS AS FACTOR Xa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |