Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 9/20 | 0.52 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 6/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175491 | 0.85 | LAP3 (0.43) | LAP3METAP1ANPEPERAP1 | |
| SCHEMBL3122525 | 0.83 | LAP3 (0.50) | LAP3METAP1 | |
| SCHEMBL4158116 | 0.81 | LAP3 (0.59) | LAP3 | |
| Oxalic Acid SCHEMBL1377705 | 0.79 | LAP3 (0.40) | LAP3METAP1ANPEP | |
| SCHEMBL19245350 | 0.78 | TRPM8 (0.35) | LAP3METAP1 | |
| SCHEMBL10755198 | 0.77 | LAP3 (0.33) | LAP3METAP1 | |
| SCHEMBL4473853 | 0.77 | LAP3 (0.33) | LAP3METAP1 | |
| SCHEMBL6014564 | 0.75 | LAP3 (0.41) | LAP3METAP1ANPEPERAP1 | |
| Methane SCHEMBL3938662 | 0.75 | LAP3 (0.32) | LAP3METAP1 | |
| SCHEMBL485995 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861107-A | ESTER INTERCHANGE OF 1,3-PROPANEDIOL COMPOUNDS WITH CARBONIC ACID ESTERS; DISTILLATIVE DEPOLYMERIZATION; CATALYSIS WITH TITANIUM OR ZIRCONIUM COMPOUND; PHOSPHORUS OR SULFUR COMPOUND STABILIZER | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-19 | — | — | US | disclosed |