Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805854 | 0.85 | CYP1A2 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1805851 | 0.85 | CYP2C19 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1807565 | 0.83 | CYP2C19 (0.42) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL9244974 | 0.83 | CYP2C19 (0.45) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1807567 | 0.83 | ALDH1A1 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1805325 | 0.81 | CYP2C19 (0.41) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL1805323 | 0.81 | CYP2C19 (0.41) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL8018423 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNA | |
| SCHEMBL1809414 | 0.80 | CYP2C19 (0.40) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL6260200 | 0.80 | CYP1A2 (0.43) | CYP2C19CYP1A2CYP3A4CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869740-A | Herbicide intermediates | ZENECA LIMITED (GB) | 1999-02-09 | — | — | US | disclosed |
| US-5659074-A | Herbicide intermediates | ZENECA LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |