SCHEMBL1809414

SCHEMBL1809414

[NH]CCc1ccc(S(=O)(=O)O)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
ALOX15 P16050 1/20 0.40
ALDH1A1 P00352 7/20 0.38
HSD17B10 Q99714 4/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
CASP6 P55212 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 2/20 0.35
TSHR P16473 3/20 0.34
NT5E P21589 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1807565 0.86 CYP2C19 (0.42) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1805323 0.84 CYP2C19 (0.41) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1805325 0.84 CYP2C19 (0.41) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1809416 0.83 TAAR1 (0.44) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL6260200 0.83 CYP1A2 (0.43) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1803280 0.81 CYP1A2 (0.39) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1803282 0.81 CA2 (0.49) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1807068 0.81 TIMP3 (0.39) CYP2C19CYP2D6ALDH1A1HSD17B10KDM4E
SCHEMBL8347649 0.80 CYP2C19 (0.43) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1805854 0.80 CYP1A2 (0.43) CYP2C19CYP1A2CYP3A4CYP2D6ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CYP2C19 887/4885CYP1A2 487/4885CYP3A4 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.