SCHEMBL8347652

SCHEMBL8347652

O=S(=O)(O)C(Cl)c1cccc(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.47
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 1/20 0.40
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
PARP1 P09874 1/20 0.38
SRC P12931 1/20 0.38
PGR P06401 1/20 0.38
DHODH Q02127 1/20 0.38
ADRB1 P08588 2/20 0.38
ADRB3 P13945 2/20 0.38
ADRB2 P07550 1/20 0.38
GBA1 P04062 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355487 0.80 ACP3 (0.47) ACP3MEN1KMT2ATSHRPARP1
SCHEMBL4589500 0.79 SRC (0.54) KMT2ATSHRSRCALDH1A1LMNA
SCHEMBL11211690 0.76 SRC (0.47) ACP3MEN1KMT2ATSHRPARP1
SCHEMBL10913344 0.75 ALDH1A1 (0.51) ACP3MEN1KMT2ATSHRALDH1A1
SCHEMBL27814107 0.74 MEN1 (0.44) ACP3MEN1KMT2APARP1GBA1
SCHEMBL19390817 0.74 ACP3 (0.48) ACP3MEN1KMT2ATSHRPGK1
SCHEMBL27551141 0.74 ACP3 (0.48) ACP3MEN1KMT2ATSHRPGK1
SCHEMBL29712699 0.73 ACP3 (0.47) ACP3MEN1KMT2ATSHRALDH1A1
SCHEMBL5318844 0.73 TSHR (0.50) ACP3MEN1KMT2ATSHRALDH1A1
SCHEMBL11614094 0.73 ACP3 (0.47) ACP3MEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869740-A Herbicide intermediates ZENECA LIMITED (GB) 1999-02-09 US disclosed
US-5659074-A Herbicide intermediates ZENECA LIMITED (GB) 1997-08-19 US disclosed