Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364665 | 0.84 | KDM4E (0.46) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL27486214 | 0.78 | PARP10 (0.61) | LMNASMN1; SMN2SRD5A2ALDH1A1PARP10 | |
| SCHEMBL7539077 | 0.77 | CTNNB1 (0.60) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL10672259 | 0.75 | FFAR1 (0.74) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL9541822 | 0.73 | CHEK2 (0.46) | LMNAKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13235754 | 0.73 | FFAR1 (0.53) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL3695003 | 0.73 | OPRM1 (0.48) | MAPTSLC6A2SLC6A3SRD5A2OPRM1 | |
| SCHEMBL1405107 | 0.72 | ALDH1A1 (0.59) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL30063523 | 0.72 | HDAC1 (0.49) | LMNAKDM4ENPC1TP53CYP1A2 | |
| SCHEMBL7325805 | 0.71 | KDM4E (0.53) | LMNAKDM4ETP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977154-A | OBESITY, DIABETES | ELI LILLY AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |