Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SCN4A | P35499 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200026 | 0.89 | TSHR (0.50) | L3MBTL1ALDH1A1SCN4ATDP1KMT2A | |
| SCHEMBL8193683 | 0.78 | TSHR (0.52) | L3MBTL1ALDH1A1SCN4ATDP1KMT2A | |
| SCHEMBL27293479 | 0.77 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1SCN4AMRGPRX4TDP1 | |
| SCHEMBL21325170 | 0.76 | SCN4A (0.74) | L3MBTL1ALDH1A1SCN4A | |
| SCHEMBL819824 | 0.73 | GLS (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL8197498 | 0.72 | TSHR (0.46) | SCN4ATDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7543571 | 0.72 | TSHR (0.46) | TDP1KMT2AKDM4EGAAMEN1 | |
| SCHEMBL5742045 | 0.71 | MEN1 (0.57) | MRGPRX4TDP1KMT2AKDM4EGAA | |
| SCHEMBL11121575 | 0.71 | KMT2A (0.61) | KMT2AKDM4EMEN1SMN1; SMN2LMNA | |
| SCHEMBL8649258 | 0.70 | SCN4A (0.55) | SCN4ATDP1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883250-A | ARYL SUBSTITUTED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| US-5679676-A | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |