⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13025566 | 0.80 | — | — | |
| SCHEMBL9286912 | 0.78 | — | — | |
| SCHEMBL14793045 | 0.76 | — | — | |
| SCHEMBL7067973 | 0.76 | — | — | |
| SCHEMBL14535983 | 0.76 | — | — | |
| SCHEMBL18951468 | 0.74 | SIGMAR1 (0.35) | — | |
| SCHEMBL3439756 | 0.73 | SIGMAR1 (0.31) | — | |
| SCHEMBL13957201 | 0.73 | SIGMAR1 (0.31) | — | |
| SCHEMBL11578211 | 0.73 | — | — | |
| SCHEMBL28729089 | 0.71 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599818-B1 | Silicon-containing resist underlayer film-forming composition and patterning process | SHINETSU CHEMICAL CO (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093028-B2 | Engineered glycosyltransferases with expanded substrate specificity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
| US-20090181854-A1 | Engineered Glycosyltransferases With Expanded Substrate Specificity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-16 | — | — | US | disclosed |
| WO-2007134485-A1 | APORPHINE AND OXOAPORPHINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | LOTUS PHARMACEUTICAL CO., LTD. (CN) | 2007-11-29 | — | — | WO | disclosed |
| WO-2003053437-A1 | TRIAZOLES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |