Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453194 | 0.82 | IDO1 (0.60) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL5695090 | 0.81 | TDP1 (0.65) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL14660487 | 0.81 | TP53 (0.57) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL5736332 | 0.80 | TDP1 (0.55) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL28694748 | 0.80 | TDP1 (0.62) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL5000643 | 0.79 | TDP1 (0.54) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL14209682 | 0.76 | MAPT (0.62) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL6273809 | 0.75 | MAPT (0.52) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL11420952 | 0.74 | RAB9A (0.62) | MAPTTSHRTDP1SMN1; SMN2HPGD | |
| SCHEMBL2421402 | 0.74 | IDO1 (0.51) | MAPTTDP1SMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016583-A1 | SUBSTITUTED GLYCINE DERIVATIVES FOR USE AS MEDICAMENTS | PFIZER LIMITED (GB) | 2004-02-26 | — | — | WO | disclosed |