Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277556 | 0.78 | NPSR1 (0.49) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL31282050 | 0.74 | NPSR1 (0.48) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL12274267 | 0.70 | CA2 (0.38) | L3MBTL1HDAC3HDAC1HDAC6PTPRC | |
| SCHEMBL28767269 | 0.69 | NPSR1 (0.46) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL70027 | 0.68 | NPSR1 (0.67) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL8549434 | 0.67 | TSHR (0.44) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL8255339 | 0.66 | HPGD (0.48) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL27589470 | 0.66 | CTSK (0.37) | L3MBTL1HDAC3HDAC1HDAC6PTPRC | |
| SCHEMBL6492852 | 0.65 | NPSR1 (0.47) | NPSR1HPGDTSHRMAPK1ATM | |
| SCHEMBL27512110 | 0.65 | EGFR (0.43) | PTPRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013130-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |