Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349062 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8347977 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8349060 | 0.88 | HTT (0.43) | ALDH1A1KDM4EHTTHPGDNPSR1 | |
| SCHEMBL8348146 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8349021 | 0.87 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL8349668 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8348056 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8348315 | 0.86 | HPGD (0.44) | ALDH1A1L3MBTL1MAPK1LMNAKMT2A | |
| SCHEMBL8350515 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EHTTL3MBTL1MAPK1 | |
| SCHEMBL8346745 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTL3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053437-A1 | TRIAZOLES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |