Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.59 |
| ▸ | CTSL | P07711 | 5/20 | 0.59 |
| ▸ | CTSV | O60911 | 3/20 | 0.59 |
| ▸ | CTSK | P43235 | 7/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 7/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219845 | 0.92 | CTSK (0.67) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL5941431 | 0.92 | CTSK (0.67) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4214766 | 0.92 | CTSK (0.67) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4214768 | 0.92 | CTSK (0.67) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL8350567 | 0.87 | CTSS (0.57) | CTSSCTSLCTSVCTSKF2RL1 | |
| SCHEMBL8349497 | 0.85 | CTSK (0.57) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL8349905 | 0.84 | CTSK (0.58) | CTSSCTSLCTSVCTSK | |
| SCHEMBL4213137 | 0.84 | CTSK (0.56) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4213141 | 0.84 | CTSK (0.56) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL5942062 | 0.84 | CTSK (0.56) | CTSSCTSLCTSVCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |