Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963551 | 0.89 | APP (0.43) | ALDH1A1L3MBTL1KMT2AMEN1GAK | |
| SCHEMBL6470818 | 0.86 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL10635279 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL11127279 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL12933421 | 0.83 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2AMEN1GAK | |
| SCHEMBL13182636 | 0.82 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10583414 | 0.81 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KMT2AMEN1HTT | |
| SCHEMBL22082131 | 0.80 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| Sulfuric Acid SCHEMBL8500882 | 0.80 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL10891966 | 0.79 | MTNR1B (0.49) | ALDH1A1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |