Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724965 | 0.91 | CHRM3 (0.36) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5724682 | 0.86 | GAA (0.34) | GAALMNASMN1; SMN2HDAC4HDAC6 | |
| SCHEMBL5726425 | 0.82 | GAA (0.41) | GAALMNASMN1; SMN2KMT2AHDAC4 | |
| SCHEMBL5724985 | 0.82 | GAA (0.41) | GAALMNASMN1; SMN2KMT2AHDAC4 | |
| SCHEMBL5725074 | 0.78 | CHRM3 (0.45) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5724973 | 0.77 | CHRM3 (0.36) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5724931 | 0.70 | CHRM3 (0.47) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL24818982 | 0.68 | GAA (0.51) | GAAKMT2ABTKALDH1A1EPHX1 | |
| SCHEMBL764580 | 0.68 | GAA (0.51) | GAAKMT2ABTKALDH1A1EPHX1 | |
| SCHEMBL15192054 | 0.68 | GAA (0.51) | GAAKMT2ABTKALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |