Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347875 | 0.89 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1HDAC1HDAC3 | |
| SCHEMBL6717373 | 0.86 | CASP2 (0.45) | SLC1A3SLC1A2SLC1A1HDAC1HDAC3 | |
| SCHEMBL6718886 | 0.86 | BRD4 (0.62) | BRD4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28609335 | 0.82 | RAB9A (0.55) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL6718687 | 0.82 | RAB9A (0.55) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL6718773 | 0.82 | RAB9A (0.55) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL6717735 | 0.81 | GAA (0.52) | BRD4ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6717424 | 0.78 | SLC1A3 (0.52) | SLC1A3SLC1A2SLC1A1HDAC1HDAC3 | |
| Formic Acid SCHEMBL6717292 | 0.77 | CYP1A2 (0.53) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6717088 | 0.77 | MEN1 (0.56) | BRD4ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |