SCHEMBL8349082

SCHEMBL8349082

NS(=O)(=O)c1ccc2cc(O)c(O)cc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
CA2 P00918 12/20 0.55
CA1 P00915 10/20 0.55
CA9 Q16790 10/20 0.55
CA12 O43570 9/20 0.55
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
PKM P14618 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
LCK P06239 1/20 0.48
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
CA4 P22748 5/20 0.45
CA6 P23280 5/20 0.45
CA5A P35218 5/20 0.45
CA7 P43166 5/20 0.45
CA14 Q9ULX7 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9839080 0.89 LMNA (0.82) LMNACA2CA1CA9CA12
SCHEMBL10879943 0.88 LMNA (0.58) LMNACA2CA1CA9CA12
SCHEMBL1805614 0.85 LMNA (0.64) LMNACA2CA1CA9CA12
SCHEMBL1805038 0.84 LMNA (0.53) LMNACA2CA1CA9CA12
SCHEMBL1802613 0.84 LMNA (0.53) LMNACA2CA1CA9CA12
SCHEMBL1806816 0.84 LMNA (0.53) LMNACA2CA1CA9CA12
SCHEMBL1806418 0.84 LMNA (0.53) LMNACA2CA1CA9CA12
SCHEMBL1805916 0.83 LMNA (0.62) LMNACA2CA1CA9CA12
SCHEMBL29419322 0.83 ALDH1A1 (0.53) LMNAKDM4ELCKALDH1A1
SCHEMBL209713 0.83 ALDH1A1 (0.53) LMNAKDM4ELCKALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935757-A HIGH COLOR DEVELOPING SENSITIVITY AND EXCELLENT STORABILITY. USING AN ESTER- OR AMIDE CONTAINING SULFOAMIDOBENZENE IN A LAYER CONTAINING A DIAZONIUM SALT AND A REACTIVE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1999-08-10 US disclosed
EP-0084890-B1 DIAZOTYPE HEAT DEVELOPMENT RECORDING MEDIUM Toppan Printing Co., Ltd. (JP) 1986-05-21 EP disclosed
US-4492749-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-08 US disclosed
EP-0017699-B1 DERIVATIVES OF 2-HYDROXY-NAPHTHALENE AND DIAZO PHOTOGRAPHIC MATERIAL CONTAINING THEM AS COUPLING COMPONENTS HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-16 EP disclosed
US-4247459-A DEVELOPERS IN ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
EP-0017699-A1 Derivatives of 2-hydroxy-naphthalene and diazo photographic material containing them as coupling components HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-29 EP disclosed
US-4145299-A GOOD DISPERSION STABILITY; LOW CONTRAST, HIGH RESOLUTION IMAGES AND LIGHT STABILITY EASTMAN KODAK COMPANY (US) 1979-03-20 US disclosed