Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351619 | 0.99 | F10 (0.41) | F10F2HRH3ITGB3ITGA2B | |
| SCHEMBL8349498 | 0.96 | F10 (0.41) | F10F2HRH3ITGB3ITGA2B | |
| SCHEMBL8355509 | 0.93 | HTR7 (0.44) | F10F2ITGB3ITGA2BHTR7 | |
| SCHEMBL8356727 | 0.89 | — | — | |
| SCHEMBL8356652 | 0.88 | ITGB3 (0.41) | HRH3ITGB3ITGA2BDRD4SLC6A4 | |
| SCHEMBL8355309 | 0.87 | HTR2B (0.47) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8355523 | 0.86 | ITGB3 (0.44) | F10F2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8351958 | 0.86 | F10 (0.42) | F10F2HRH3ITGB3ITGA2B | |
| SCHEMBL8352588 | 0.85 | ITGB3 (0.39) | HRH3ITGB3ITGA2BDRD4SLC6A4 | |
| SCHEMBL8356627 | 0.83 | GRM2 (0.34) | F10F2HRH3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |