Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855278 | 1.00 | MAPT (0.46) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8351699 | 0.85 | MEN1 (0.63) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8351696 | 0.85 | MEN1 (0.63) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7845703 | 0.85 | ALDH1A1 (0.48) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL10479312 | 0.85 | CYP3A4 (0.48) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL10479311 | 0.85 | CYP3A4 (0.48) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8350180 | 0.85 | ALDH1A1 (0.48) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL7856609 | 0.82 | CYP3A4 (0.46) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8351681 | 0.82 | CYP3A4 (0.46) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL8189209 | 0.81 | CYP1A2 (0.45) | MAPTMEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942506-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, ANXIETY | GIS GYOGYSZERGYAR RT. (HU) | 1999-08-24 | — | — | US | disclosed |