SCHEMBL8350323

SCHEMBL8350323

COC(=O)c1ccc([O])c(NC(C)=O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.69
HDAC1 Q13547 1/20 0.54
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 12/20 0.49
HSD17B10 Q99714 4/20 0.49
HPGD P15428 4/20 0.49
CASP1 P29466 2/20 0.49
CASP7 P55210 2/20 0.49
CYP2C9 P11712 1/20 0.49
TSHR P16473 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
XDH P47989 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
PIK3CA P42336 1/20 0.48
PIK3CB P42338 1/20 0.48
PIK3CG P48736 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958854 0.84 KMT2A (0.61) ALDH1A1KMT2AKDM4EHPGDCA12
SCHEMBL30487008 0.83 KDM4E (0.69) ALDH1A1KMT2AKDM4EHSD17B10HPGD
SCHEMBL7420862 0.83 ALDH1A1 (0.69) ALDH1A1HDAC1KMT2AKDM4EHSD17B10
SCHEMBL13088436 0.83 KDM4E (0.69) ALDH1A1KMT2AKDM4EHSD17B10HPGD
SCHEMBL9436316 0.83 ALDH1A1 (0.69) ALDH1A1HDAC1KMT2AHPGDCYP2C9
SCHEMBL9336136 0.82 NEU3 (0.54) ALDH1A1HDAC1KMT2AKDM4EHSD17B10
SCHEMBL18737953 0.81 ALDH1A1 (0.67) ALDH1A1HDAC1KMT2AKDM4EHSD17B10
SCHEMBL11643272 0.81 ALDH1A1 (0.67) ALDH1A1HDAC1KMT2AKDM4EHSD17B10
SCHEMBL7920947 0.81 ALDH1A1 (0.67) ALDH1A1HDAC1KMT2AKDM4EHSD17B10
SCHEMBL19342980 0.81 ALDH1A1 (0.67) ALDH1A1HDAC1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962208-A Silver halide color photographic material containing a yellow coupler and a mercapto compound FUJI PHOTO FILM CO., LTD. (JP) 1999-10-05 US disclosed
EP-0472153-B1 A silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-03-05 EP disclosed
EP-0459458-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-02-12 EP disclosed
EP-0427225-B1 Direct positive color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
US-5498513-A BENZOTRIAZOLE DIR COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1996-03-12 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5298374-A Hydrophilic colloid layer on paper with epoxy compounds such as epoxy resins or glycidol modified phenol-formaldehyde resin FUJI PHOTO FILM CO., LTD. (JP) 1994-03-29 US disclosed
US-5268261-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-07 US disclosed
US-5217857-A High speed color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1993-06-08 US disclosed
US-5153107-A 2-equivalent yellow and pyrazoloazole magenta couplers FUJI PHOTO FILM CO., LTD. (JP) 1992-10-06 US disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
EP-0472153-A1 A silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1992-02-26 EP disclosed
EP-0459458-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-04 EP disclosed
EP-0427225-A1 Direct positive color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-05-15 EP disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed