Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218090 | 0.86 | ALDH1A1 (0.64) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL8959475 | 0.85 | CA12 (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL28455641 | 0.85 | CA12 (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL8958864 | 0.84 | CA12 (0.64) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1544846 | 0.84 | POLB (0.57) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL8350323 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL9436316 | 0.83 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2HPGDLMNAKMT2A | |
| SCHEMBL13088436 | 0.83 | KDM4E (0.69) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL30487008 | 0.83 | KDM4E (0.69) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL1390872 | 0.82 | KDM4E (0.53) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2024-01-18 | — | — | US | disclosed |
| EP-0820441-B1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6358992-B1 | Method of inhibiting neoplastic cells with indole derivatives | CELL PATHWAYS, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6069156-A | Indole derivatives as cGMP-PDE inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| US-5962208-A | Silver halide color photographic material containing a yellow coupler and a mercapto compound | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |
| EP-0472153-B1 | A silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0459458-B1 | Silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1996032379-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-17 | — | — | WO | disclosed |
| EP-0317983-B1 | Silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5298374-A | Hydrophilic colloid layer on paper with epoxy compounds such as epoxy resins or glycidol modified phenol-formaldehyde resin | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5268261-A | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-07 | — | — | US | disclosed |
| US-5217857-A | High speed color reproduction | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5153107-A | 2-equivalent yellow and pyrazoloazole magenta couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5100771-A | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0472153-A1 | A silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0459458-A1 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-04 | — | — | EP | disclosed |
| EP-0427225-A1 | Direct positive color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0317983-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018153-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | ABCG2, ABCB1, ARSA | ALDH1A1 653/4885CA12 2893/4885CA1 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.