Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | PREP | P48147 | 1/20 | 0.55 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349856 | 0.94 | CTSK (0.62) | DPP4PREPFAPCTSKACHE | |
| SCHEMBL13909124 | 0.79 | CTSK (0.63) | DPP4PREPFAPCTSKCTSS | |
| SCHEMBL13909135 | 0.78 | CTSK (0.55) | DPP4PREPFAPCTSKCTSS | |
| SCHEMBL8347301 | 0.77 | CTSK (0.68) | DPP4PREPFAPCTSKCTSS | |
| SCHEMBL6211132 | 0.77 | CTSK (0.52) | DPP4CTSKACHECTSSCNR2 | |
| SCHEMBL8348491 | 0.75 | CTSK (0.48) | DPP4PREPFAPCTSKITGB3 | |
| SCHEMBL13909142 | 0.74 | CTSK (0.48) | PREPCTSKCTSS | |
| SCHEMBL5941982 | 0.74 | CTSK (0.72) | CTSKCTSS | |
| SCHEMBL5941978 | 0.74 | CTSK (0.72) | CTSKCTSS | |
| SCHEMBL4048380 | 0.74 | CTSK (0.64) | DPP4FAPCTSKCTSSCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |