Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312097 | 0.78 | TAAR1 (0.46) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL27612097 | 0.76 | ALDH1A1 (0.45) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| SCHEMBL8351459 | 0.76 | NAMPT (0.58) | KMT2AALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL8346288 | 0.75 | TAAR1 (0.45) | KMT2AALDH1A1TDP1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL10925225 | 0.74 | MEN1 (0.48) | KMT2AALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL3069963 | 0.71 | ALDH1A1 (0.80) | KMT2AALDH1A1KDM4EPKMTSHR | |
| SCHEMBL16373567 | 0.70 | HTT (0.74) | KMT2AALDH1A1TDP1L3MBTL1HPGD | |
| SCHEMBL8150783 | 0.70 | CD274 (0.85) | ALDH1A1KDM4EHPGDTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10927054 | 0.70 | KMT2A (0.57) | KMT2AALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL8345399 | 0.69 | HDAC3 (0.41) | KDM4EHPGDSMN1; SMN2KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935776-A | 2,5-BIS(4-(3-N,N,-DIMETHYLAMINOPROPYLAMIDINO)PHENYL)FURAN OR PHARMACEUTICALLY ACCEPTABLE SALT AND DILUENT OR CARRIER AS VIRICIDE TO SUPPRESS BINDING OF REV PROTEIN TO MESSENGER RNAS THUS SUPPRESSING REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1999-08-10 | — | — | US | claimed |
| US-5935776-A | 2,5-BIS(4-(3-N,N,-DIMETHYLAMINOPROPYLAMIDINO)PHENYL)FURAN OR PHARMACEUTICALLY ACCEPTABLE SALT AND DILUENT OR CARRIER AS VIRICIDE TO SUPPRESS BINDING OF REV PROTEIN TO MESSENGER RNAS THUS SUPPRESSING REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1999-08-10 | — | — | US | disclosed |