Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.46 |
| ▸ | PPARA | Q07869 | 13/20 | 0.46 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354923 | 0.80 | PPARG (0.46) | PPARGPPARAC3AR1FOLH1PTGES | |
| SCHEMBL8356673 | 0.78 | PPARG (0.47) | PPARGPPARAFOLH1PTGESALOX5 | |
| SCHEMBL8350734 | 0.77 | PPARG (0.46) | PPARGPPARAFOLH1PTGESALOX5 | |
| SCHEMBL8965129 | 0.73 | PTGDR2 (0.55) | PPARGPPARAPTGDR2 | |
| SCHEMBL8355205 | 0.73 | PPARG (0.46) | PPARGPPARAFOLH1PTGESALOX5 | |
| SCHEMBL8414123 | 0.72 | C3AR1 (0.33) | C3AR1 | |
| SCHEMBL8965331 | 0.72 | PTGDR2 (0.39) | PPARGPPARAPTGDR2 | |
| SCHEMBL9614256 | 0.72 | PPARG (0.81) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL8356620 | 0.71 | PPARG (0.47) | PPARGPPARAC3AR1FOLH1PTGES | |
| SCHEMBL8358614 | 0.70 | MEN1 (0.48) | PPARGPPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |