Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358614 | 0.85 | MEN1 (0.48) | PTGDR2PTGDRPPARGPPARAKMT2A | |
| SCHEMBL8965129 | 0.84 | PTGDR2 (0.55) | PTGDR2PTGDRPPARGPPARACYSLTR2 | |
| SCHEMBL8965293 | 0.82 | PKM (0.45) | PTGDR2ACHEPTGDRMTNR1AMTNR1B | |
| SCHEMBL8350655 | 0.72 | ALDH1A1 (0.38) | PPARGPPARAKMT2AALDH1A1MAPT | |
| SCHEMBL1789805 | 0.72 | PPARA (0.56) | ACHEPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL8350653 | 0.72 | PPARG (0.46) | PTGDR2PPARGPPARA | |
| SCHEMBL28337010 | 0.71 | PPARA (0.62) | ACHEPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL29328696 | 0.70 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL31539531 | 0.70 | CYP4F2 (0.54) | ACHEPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL28593564 | 0.69 | ACHE (0.58) | ACHEPPARGPPARAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |