Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 11/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350894 | 1.00 | PRKCA (0.46) | PRKCASIRT2LMNATSHR | |
| SCHEMBL8350889 | 0.69 | PRKCA (0.51) | PRKCASIRT2LMNATSHR | |
| SCHEMBL11438921 | 0.65 | — | — | |
| SCHEMBL13566289 | 0.65 | — | — | |
| SCHEMBL1165003 | 0.65 | — | — | |
| SCHEMBL919332 | 0.65 | — | — | |
| SCHEMBL18687969 | 0.65 | SIRT2 (0.34) | PRKCASIRT2LMNATSHR | |
| SCHEMBL28750826 | 0.65 | — | — | |
| SCHEMBL15199798 | 0.65 | SIRT2 (0.37) | PRKCASIRT2 | |
| SCHEMBL26566738 | 0.63 | PRKCA (0.54) | PRKCASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874464-A | ANTAGONIST OF PROTEIN KINASE C | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-02-23 | — | — | US | disclosed |