Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406965 | 0.96 | TP53 (0.62) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8080249 | 0.94 | TP53 (0.65) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8072237 | 0.94 | TP53 (0.65) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8081520 | 0.94 | TP53 (0.65) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8081503 | 0.94 | TP53 (0.65) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8081129 | 0.94 | TP53 (0.65) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL8984333 | 0.92 | L3MBTL1 (0.56) | TSHRLMNACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL8292097 | 0.88 | TP53 (0.61) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL14097166 | 0.87 | RARB (0.57) | TP53TSHRLMNANPC1CYP1A2 | |
| SCHEMBL9650326 | 0.86 | NPC1 (0.72) | TP53TSHRLMNANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805038-B | Synthesis method of poly (p-phenylene ethylene) photoelectric material intermediate | 荆州市天翼精细化工开发有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-108812681-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2021-02-26 | — | — | CN | disclosed |
| US-8709280-B2 | Polar nematic compounds | VANDERBILT UNIVERSITY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | VANDERBILT UNIVERSITY | 2012-10-04 | — | — | US | disclosed |
| US-20070060748-A1 | Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure | ARTESIAN THERAPEUTICS, INC. | 2007-03-15 | — | — | US | disclosed |
| WO-2004050657-A2 | COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE | ARTESIAN THERAPEUTICS, INC. (US) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248373-A1 | POLAR NEMATIC COMPOUNDS | LATS2, CCNH, CRY1 | TP53 3616/4885TSHR 1927/4885LMNA 2035/4885 |
| US-20070060748-A1 | Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure | ADRB3, PDE3A, PDE3B | TP53 4834/4885TSHR 878/4885LMNA 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.