Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685746 | 0.93 | MEN1 (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL10684217 | 0.92 | KDM4C (0.50) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL10683252 | 0.91 | MEN1 (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12634794 | 0.88 | KDM4C (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12634793 | 0.83 | KDM4C (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12635021 | 0.81 | MEN1 (0.41) | KDM4CMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL12635025 | 0.81 | ADRB2 (0.43) | KDM4CMEN1KMT2AADRB2ADRB1 | |
| SCHEMBL10683573 | 0.80 | HTR1A (0.48) | KDM4CMEN1KMT2AL3MBTL1DRD2 | |
| SCHEMBL10679721 | 0.80 | MEN1 (0.47) | KDM4CMEN1KMT2AL3MBTL1ADRB2 | |
| SCHEMBL10683368 | 0.80 | MEN1 (0.47) | KDM4CMEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |