Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.39 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021481 | 0.86 | POLB (0.46) | EGFRSMN1; SMN2PIP4K2APIP4K2BTGM2 | |
| SCHEMBL13389249 | 0.83 | EGFR (0.55) | EGFRJAK3ITKSMN1; SMN2PIP4K2A | |
| SCHEMBL23336395 | 0.82 | PIP4K2A (0.36) | KDM4EEGFRJAK3ITKSMN1; SMN2 | |
| SCHEMBL19450424 | 0.79 | TGM2 (0.42) | KDM4ESMN1; SMN2TGM2NPC1RAB9A | |
| SCHEMBL14016448 | 0.75 | TGM2 (0.45) | KDM4ECYP1A2EGFRSMN1; SMN2TGM2 | |
| SCHEMBL21414659 | 0.73 | TGM2 (0.48) | KDM4ECYP1A2EGFRSMN1; SMN2TGM2 | |
| SCHEMBL23997975 | 0.72 | KDM4E (0.36) | KDM4E | |
| SCHEMBL12942208 | 0.72 | EGFR (0.46) | KDM4ECYP1A2EGFRSMN1; SMN2TAS2R38 | |
| SCHEMBL21944495 | 0.70 | MAOB (0.42) | KDM4EEGFRSMN1; SMN2TGM2NPC1 | |
| SCHEMBL22700707 | 0.70 | TGM2 (0.46) | KDM4ECYP1A2EGFRSMN1; SMN2TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020266-A1 | ANTINEOPLASTIC COMBINATIONS | WYETH (US) | 2003-03-13 | — | — | WO | disclosed |