Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 7/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351065 | 1.00 | CTSS (0.56) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL13043245 | 0.89 | CTSK (0.46) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL22962299 | 0.88 | CTSS (0.70) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10135746 | 0.88 | CTSS (0.70) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10135530 | 0.86 | CTSS (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL13043257 | 0.84 | CTSK (0.56) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL12947678 | 0.84 | CTSK (0.54) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10195698 | 0.84 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10135741 | 0.84 | CTSK (0.55) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL14637585 | 0.84 | CTSK (0.55) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319540-A1 | Sustained release pharmaceutical compounds to prevent abuse of controlled substances | Shire LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2003072046-A2 | NOVEL SUSTAINED RELEASE PHARMACEUTICAL COMPOUNDS TO PREVENT ABUSE OF CONTROLLED SUBSTANCES | NEW RIVER PHARMACEUTICALS INC. (US) | 2003-09-04 | — | — | WO | disclosed |