Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 20/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.48 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351173 | 0.92 | PLA2G1B (0.52) | PLA2G1BPLA2G2APLA2G5PLA2G2EPLA2G10 | |
| SCHEMBL9082881 | 0.92 | PLA2G1B (0.51) | PLA2G1BPLA2G2APLA2G5PLA2G2EPLA2G10 | |
| SCHEMBL8025842 | 0.90 | PLA2G1B (0.64) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL9080609 | 0.84 | PLA2G1B (0.47) | PLA2G1BPLA2G2APLA2G5PLA2G2EPLA2G10 | |
| SCHEMBL8026001 | 0.84 | PLA2G1B (0.54) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL8022479 | 0.81 | PLA2G1B (0.53) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL8079807 | 0.80 | PLA2G1B (0.68) | PLA2G1BPLA2G2A | |
| SCHEMBL8507738 | 0.78 | PLA2G1B (0.68) | PLA2G1BPLA2G2A | |
| SCHEMBL8327335 | 0.78 | PLA2G1B (0.42) | PLA2G1B | |
| SCHEMBL14614219 | 0.78 | PLA2G1B (0.76) | PLA2G1BPLA2G2APLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999024033-A1 | METHOD FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH APOPTOSIS USING N-HETEROCYCLIC GLYOXYLAMIDE COMPOUNDS | SHIONOGI & CO., LTD. (JP) | 1999-05-20 | — | — | WO | claimed |
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |