Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081139 | 0.89 | PLA2G1B (0.45) | PLA2G1BALDH1A1HTTPLA2G2APLA2G5 | |
| SCHEMBL8352190 | 0.84 | PLA2G1B (0.61) | PLA2G1BPLA2G10PLA2G2APLA2G5PLA2G2E | |
| SCHEMBL8327335 | 0.82 | PLA2G1B (0.42) | PLA2G1BALDH1A1HTTLMNANPSR1 | |
| SCHEMBL9081699 | 0.77 | PLA2G1B (0.49) | PLA2G1BALDH1A1PLA2G2ALMNAKDM4E | |
| SCHEMBL9080332 | 0.75 | PLA2G2A (0.52) | PLA2G1BPLA2G10PLA2G2APLA2G5PLA2G2E | |
| SCHEMBL8025842 | 0.73 | PLA2G1B (0.64) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL7006970 | 0.73 | PLA2G1B (0.71) | PLA2G1BPLA2G10PLA2G2APLA2G5PLA2G2E | |
| SCHEMBL8026001 | 0.72 | PLA2G1B (0.54) | PLA2G1BPLA2G2APLA2G5PLA2G2E | |
| SCHEMBL9081766 | 0.70 | PLA2G1B (0.52) | PLA2G1BPLA2G10PLA2G2APLA2G5PLA2G2E | |
| SCHEMBL9081375 | 0.68 | PLA2G1B (0.71) | PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |