Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039850 | 0.88 | HIF1A (0.49) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL8356175 | 0.81 | ALOX5 (0.52) | HIF1AALOX5PTGS2CYP2D6TSHR | |
| SCHEMBL16963068 | 0.81 | ALOX5 (0.45) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL17656826 | 0.81 | ALOX5 (0.45) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL14883383 | 0.81 | ALOX5 (0.45) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL19628264 | 0.81 | HIF1A (0.52) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL14866128 | 0.80 | CA12 (0.58) | HIF1ACYP1A2CA12CA2KDM4E | |
| SCHEMBL7100079 | 0.80 | CA12 (0.58) | HIF1ACYP1A2CA12CA2KDM4E | |
| SCHEMBL3998710 | 0.78 | ALOX5 (0.51) | HIF1AALOX5PTGS2CYP2C19CYP1A2 | |
| SCHEMBL29785796 | 0.78 | ALOX5 (0.51) | HIF1AALOX5PTGS2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998645-A | LAUNDERING DETERGENTS; CLEANING COMPOUNDS | CLARIANT GMBH (DE) | 1999-12-07 | — | — | US | disclosed |