Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628267 | 0.94 | HIF1A (0.51) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL19628265 | 0.88 | HIF1A (0.42) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL25039850 | 0.86 | HIF1A (0.49) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL8352502 | 0.81 | HIF1A (0.53) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL16963068 | 0.73 | ALOX5 (0.45) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL17656826 | 0.73 | ALOX5 (0.45) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL14883383 | 0.73 | ALOX5 (0.45) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL6053413 | 0.73 | HIF1A (0.59) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL14804453 | 0.71 | ALOX5 (0.43) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL20810350 | 0.71 | HIF1A (0.47) | HIF1ACYP2C19CYP2D6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335061-A1 | ISOTACTIC POLYETHERS AND BIMETALLIC CATALYSTS, METHODS OF MAKING SAME, AND USES THEREOF | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170335061-A1 | ISOTACTIC POLYETHERS AND BIMETALLIC CATALYSTS, METHODS OF MAKING SAME, AND USES THEREOF | SQLE, PAOX, AGL | HIF1A 4222/4885CYP2C19 2162/4885CYP2D6 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.