Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12519914 | 0.98 | RAB9A (0.56) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 | |
| SCHEMBL8348678 | 0.84 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1CYP2C19HTT | |
| SCHEMBL16303842 | 0.82 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 | |
| SCHEMBL15014635 | 0.81 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1MAPK1HTT | |
| SCHEMBL23277862 | 0.80 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 | |
| SCHEMBL12963698 | 0.79 | NPC1 (0.52) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 | |
| SCHEMBL12933353 | 0.77 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 | |
| SCHEMBL12384751 | 0.77 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1MAPK1HTT | |
| SCHEMBL15014518 | 0.75 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL3427885 | 0.75 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |