Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.61 |
| ▸ | MMP14 | P50281 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386986 | 0.94 | MMP13 (0.70) | MMP13MMP14 | |
| SCHEMBL6388821 | 0.89 | MMP13 (0.74) | MMP13MMP14 | |
| SCHEMBL6386044 | 0.81 | MMP13 (0.70) | MMP13MMP14 | |
| SCHEMBL6389586 | 0.81 | MMP13 (0.73) | MMP13MMP14 | |
| SCHEMBL6388193 | 0.81 | MMP13 (0.73) | MMP13MMP14 | |
| SCHEMBL6388181 | 0.81 | MMP13 (0.73) | MMP13MMP14 | |
| SCHEMBL6388877 | 0.80 | MMP13 (0.72) | MMP13MMP14 | |
| SCHEMBL6386945 | 0.80 | MMP13 (0.72) | MMP13MMP14 | |
| SCHEMBL6386001 | 0.80 | MMP14 (0.65) | MMP13MMP14 | |
| SCHEMBL6388827 | 0.79 | MMP13 (0.68) | MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002034726-A9 | PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS | PFIZER PROD INC (US) | 2003-03-06 | — | — | WO | disclosed |