Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108090 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL2685255 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL29519211 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9300407 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9303010 | 0.74 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL13920494 | 0.71 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL14446987 | 0.67 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL9387451 | 0.67 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL14195268 | 0.66 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL13696695 | 0.66 | ALOX5 (0.78) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343769-B1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-1511737-B1 | ARYLOXIMES | MERCK PATENT GMBH (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1509506-B1 | PYRIDAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |
| WO-2003104205-A1 | ARYLOXIMES | MERCK PATENT GMBH (DE) | 2003-12-18 | — | — | WO | disclosed |
| WO-2003039548-A1 | HYDRAZONO-MALONITRILES | MERCK PATENT GMBH (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003037349-A1 | TYPE 4 PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2003-05-08 | — | — | WO | disclosed |