Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519211 | 1.00 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9303010 | 0.89 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9387577 | 0.88 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL30108090 | 0.86 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL2685255 | 0.86 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL13920494 | 0.79 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL9258913 | 0.79 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL14446987 | 0.79 | ALOX5 (0.87) | ALOX5 | |
| SCHEMBL8353043 | 0.78 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9381761 | 0.77 | ALOX5 (0.68) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308852-A | Cardiovascular disorders | MERCK FROSST CANADA, INC. (CA) | 1994-05-03 | — | — | US | disclosed |