Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549845 | 0.76 | HTR6 (0.62) | HTR6 | |
| SCHEMBL29277536 | 0.74 | HTR6 (0.43) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL29277542 | 0.74 | HTR6 (0.43) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL8358058 | 0.71 | PIK3CA (0.40) | ALDH1A1KDM4EMAPTHTR6GRM5 | |
| SCHEMBL8353263 | 0.67 | PTGS2 (0.41) | ALDH1A1KDM4ELMNAMAPTHTR6 | |
| SCHEMBL5422878 | 0.66 | CYP2A6 (0.48) | ALDH1A1KDM4ELMNAMAPTHTR6 | |
| SCHEMBL13721413 | 0.65 | ATM (0.51) | ALDH1A1KDM4ELMNAMAPTHTR6 | |
| SCHEMBL26259377 | 0.63 | KDM4E (0.50) | ALDH1A1KDM4ELMNAMAPTHTR6 | |
| SCHEMBL13720590 | 0.62 | TP53 (0.41) | ALDH1A1KDM4EHTR6KMT2ATP53 | |
| SCHEMBL6693894 | 0.61 | HTR6 (0.59) | ALDH1A1KDM4EMAPTHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959107-A | Isoquinoline derivatives | SNOW BRAND MILK PRODUCTS CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |