Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201140 | 0.95 | — | — | |
| SCHEMBL29509677 | 0.93 | CYP2C19 (0.56) | CYP2C19MEN1KMT2AFFAR3HDAC3 | |
| Hydrochloric Acid SCHEMBL6778693 | 0.92 | — | — | |
| Propionic Acid SCHEMBL27438807 | 0.88 | FFAR3 (0.48) | CYP2C19MEN1KMT2AFFAR3HDAC3 | |
| SCHEMBL12491912 | 0.87 | LMNA (0.50) | KMT2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL5035377 | 0.87 | LMNA (0.50) | KMT2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL162041 | 0.87 | LMNA (0.50) | KMT2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL20415450 | 0.87 | LMNA (0.50) | KMT2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL17433002 | 0.87 | LMNA (0.50) | KMT2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL6202153 | 0.85 | CYP2C19 (0.43) | CYP2C19MEN1KMT2AFFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011115-A2 | PEPTIDE-BASED MULTIMERIC TARGETED CONTRAST AGENTS | EPIX MEDICAL, INC. (US) | 2003-02-13 | — | — | WO | disclosed |