Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.66 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | TDP2 | O95551 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | NMT1 | P30419 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353487 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL2831352 | 0.85 | ALDH1A1 (0.79) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1683255 | 0.85 | ALDH1A1 (0.79) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1169889 | 0.85 | ALDH1A1 (0.79) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11133691 | 0.85 | LPAR2 (0.88) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11137034 | 0.85 | LPAR2 (0.88) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7858424 | 0.84 | LPAR2 (0.72) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7858420 | 0.84 | LPAR2 (0.72) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9360711 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29262225 | 0.83 | ALDH1A1 (0.76) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758314-B1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LTD (GB) | 1999-09-15 | — | — | EP | claimed |
| US-5877204-A | Compounds containing a michael-acceptor, especially maleimide or maleic acid derivatives, directly or indirectly linked to a chromophore and their use in long lasting sunscreen compositions | VANGUARD MEDICA LIMITED (GB) | 1999-03-02 | — | — | US | claimed |
| EP-0758314-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | Vanguard Medica Limited (GB) | 1997-02-19 | — | — | EP | claimed |
| WO-1995030646-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LIMITED (GB) | 1995-11-16 | — | — | WO | claimed |
| EP-0758314-B1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LTD (GB) | 1999-09-15 | — | — | EP | disclosed |
| US-5877204-A | Compounds containing a michael-acceptor, especially maleimide or maleic acid derivatives, directly or indirectly linked to a chromophore and their use in long lasting sunscreen compositions | VANGUARD MEDICA LIMITED (GB) | 1999-03-02 | — | — | US | disclosed |
| EP-0758314-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | Vanguard Medica Limited (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030646-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |