SCHEMBL2831352

SCHEMBL2831352

O=C(O)/C=C/C(=O)Nc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.79
MAPT P10636 6/20 0.79
KDM4E B2RXH2 3/20 0.79
LPAR2 Q9HBW0 2/20 0.78
LPAR1 Q92633 1/20 0.78
LPAR3 Q9UBY5 2/20 0.74
MEN1 O00255 1/20 0.73
KMT2A Q03164 1/20 0.73
L3MBTL1 Q9Y468 2/20 0.71
TDP2 O95551 1/20 0.71
GAA P10253 1/20 0.71
THRB P10828 1/20 0.71
NMT1 P30419 1/20 0.69
HTT P42858 1/20 0.67
RECQL P46063 1/20 0.67
POLB P06746 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
EGFR P00533 1/20 0.66
MMP1 P03956 1/20 0.66
MMP2 P08253 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683255 1.00 ALDH1A1 (0.79) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL1169889 1.00 ALDH1A1 (0.79) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL29262225 0.98 ALDH1A1 (0.76) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL15667293 0.98 ALDH1A1 (0.76) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL9360711 0.98 ALDH1A1 (0.76) ALDH1A1MAPTKDM4ELPAR2LPAR1
Cyclohexane SCHEMBL11782389 0.94 ALDH1A1 (0.71) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL6302452 0.93 MMP1 (0.73) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL9840923 0.93 MMP1 (0.73) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL6302448 0.93 MMP1 (0.73) ALDH1A1MAPTKDM4ELPAR2LPAR1
SCHEMBL4937846 0.92 ALDH1A1 (0.74) ALDH1A1MAPTKDM4ELPAR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2690116-B1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME NIPPON CATALYTIC CHEM IND (JP) 2019-08-07 EP claimed
US-9631033-B2 N-phenylmaleimide compound and copolymer composition obtained using same NIPPON SHOKUBAI CO., LTD. (JP) 2017-04-25 US claimed
EP-2690116-A1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME Nippon Shokubai Co., Ltd. (JP) 2014-01-29 EP claimed
US-20140011959-A1 N-PHENYLMALEIMIDE COMPOUND AND COPOLYMER COMPOSITION OBTAINED USING SAME NIPPON SHOKUBAI CO., LTD. (JP) 2014-01-09 US claimed
US-8357353-B2 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2013-01-22 US claimed
US-20100215600-A1 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2010-08-26 US claimed
US-7727514-B2 Compositions comprising a UV-absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2010-06-01 US claimed
US-7572610-B2 Methods of making compositions comprising a UV-Absorbing chromophore BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2009-08-11 US claimed
EP-2040552-A2 FORMULATIONS WITH FERULOYL GLYCERIDES AND METHODS OF PREPARATION BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION (US) 2009-04-01 EP claimed
EP-1948318-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE AND METHODS OF MAKING AND USING SAME BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION (US) 2008-07-30 EP claimed
US-20080050321-A1 Formulations with Feruloyl Glycerides and Methods of Preparation BIOTECH RESEARCH AND DEVELOPMENT CORPORATION (US) 2008-02-28 US claimed
WO-2008003090-A2 FORMULATIONS WITH FERULOYL GLYCERIDES AND METHODS OF PREPARATION BIOTECH RESEARCH AND DEVELOPMENT CORPORATION (US) 2008-01-03 WO claimed
WO-2007041424-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE AND METHODS OF MAKING AND USING SAME BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2007-04-12 WO claimed
US-20070077214-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2007-04-05 US claimed
US-20070077636-A1 METHODS OF MAKING COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE BIOTECHNOLOGY RESEARCH & DEVELOPMENT CORPORATION (US) 2007-04-05 US claimed
US-4001149-A Novel fire-retardant polymer THE DOW CHEMICAL COMPANY (US) 1977-01-04 US claimed
JP-8143559-A None JP disclosed
EP-4687812-A2 FORMULATIONS AND APPLICATIONS OF FERULOYL GLYCERIDES Midwest Bioprocessing Center, LLC (US) 2026-02-11 EP disclosed
US-4008186-A Novel fire-retardant polymer THE DOW CHEMICAL COMPANY (US) 1977-02-15 US disclosed
US-4001149-A Novel fire-retardant polymer THE DOW CHEMICAL COMPANY (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080050321-A1 Formulations with Feruloyl Glycerides and Methods of Preparation F2, F10, F12 ALDH1A1 1042/4885MAPT 2854/4885KDM4E 3194/4885
US-20070077214-A1 COMPOSITIONS COMPRISING A UV-ABSORBING CHROMOPHORE CRY2, ERCC4, CCNB2 ALDH1A1 1206/4885MAPT 2175/4885KDM4E 3088/4885
US-20100215600-A1 Compositions comprising a UV-absorbing chromophore CRY2, ERCC4, CCNB2 ALDH1A1 1206/4885MAPT 2175/4885KDM4E 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.