Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.38 |
| ▸ | RXRG | P48443 | 16/20 | 0.38 |
| ▸ | RXRB | P28702 | 15/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353210 | 0.85 | RXRA (0.45) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8556722 | 0.85 | RXRA (0.43) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8555716 | 0.84 | RXRA (0.44) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8556430 | 0.81 | RXRA (0.43) | RXRARXRGRXRB | |
| SCHEMBL8555449 | 0.81 | RXRA (0.43) | RXRARXRGRXRB | |
| SCHEMBL8555508 | 0.81 | RXRA (0.43) | RXRARXRGRXRB | |
| SCHEMBL8557645 | 0.81 | RXRA (0.43) | RXRARXRGRXRB | |
| SCHEMBL8347055 | 0.81 | RXRA (0.43) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8559129 | 0.80 | RXRA (0.45) | RXRARXRGRXRBRARGRARA | |
| SCHEMBL8347102 | 0.78 | RXRA (0.40) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | claimed |