Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354101 | 0.88 | SLC27A1 (0.66) | ALDH1A1KDM4EKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8354234 | 0.87 | ALDH1A1 (0.76) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8356375 | 0.85 | ALDH1A1 (0.75) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8353473 | 0.85 | ALDH1A1 (0.72) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8353613 | 0.84 | ALDH1A1 (0.74) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8354632 | 0.84 | SMN1; SMN2 (0.85) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8351312 | 0.83 | ALDH1A1 (0.76) | ALDH1A1POLBKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL8358101 | 0.83 | SMN1; SMN2 (0.84) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8353119 | 0.83 | ALDH1A1 (0.74) | ALDH1A1POLBKDM4EKMT2ATSHR | |
| SCHEMBL8350662 | 0.82 | ALDH1A1 (0.70) | ALDH1A1POLBKDM4EKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |