Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600248 | 0.97 | TLR2 (0.59) | TLR2KMT2AMDM2TNFMDM4 | |
| SCHEMBL26310450 | 0.95 | KMT2A (0.58) | TLR2KMT2AMDM2SIRT2SIRT1 | |
| SCHEMBL4600667 | 0.94 | TLR2 (0.60) | TLR2KMT2AMDM2TNFMDM4 | |
| SCHEMBL29528567 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL260631 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL29401258 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL178733 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL29359997 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL178698 | 0.92 | KMT2A (0.66) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL30272949 | 0.90 | KMT2A (0.56) | TLR2KMT2AMDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5879898-A | DETECTION OF CD44 PROTEINS AND FOR THE IN VIVO IMAGING AND THERAPY OF TUMORS. | ISIS INNOVATION LIMITED (GB) | 1999-03-09 | — | — | US | disclosed |